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Product Details
| Description | 3-Biphenylboronic acid is a biochemical for proteomics research |
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Uses |
3-Biphenylboronic Acid is a fluorescent boronic acid useful for sensitive detection of sugars in water. Boronic acids, including 3-Biphenylboronic acid, are valuable in organic synthesis, particularly in reactions like Suzuki-Miyaura cross-coupling reactions. These reactions are widely used for the formation of carbon-carbon bonds. |
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Chemical Properties |
yellow crystal powder |
| Canonical SMILES | B(C1=CC(=CC=C1)C2=CC=CC=C2)(O)O |
| Exact Mass | 198.0852098 g/mol |
| Monoisotopic Mass | 198.0852098 g/mol |
| Complexity | 190 |
InChI:InChI=1/C12H11BO2/c14-13(15)12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-9,14-15H
On the basis of molecular shape selectivity assumption, we initially expected that phenylboronic acid would be converted; while 3-biphenylboronic acid would not. However, as shown …
Epimerisation between ribofuranose and arabinofuranose sugars is crucial in several biosynthetic pathways, but is typically challenging to monitor. Here, we have screened for fluorescent boronic acids that can be used as molecular probes for the specific detection of ribofuranose over arabinofuranose sugars in solution. We show excellent specificity of the fluorescent response of 3-biphenylboronic acid to ribofuranose at physiological pH. This provides a tool for in situ monitoring of carbohydrate modifying enzymes and provides a viable alternative to traditional radiolabelled assays.
(Chemical Equation Presented) Step by st...
boric acid tributyl ester
[(1,1'-biphenyl)-3-yl]magnesium bromide
Trimethyl borate
3-bromobiphenyl
2,6-Bis-biphenyl-3-yl-pyridine
2''-amino-m-quinquephenyl
2-(acetylamino)-5-benzyl-3-(3-biphenylyl)pyridine N-oxide
2-(acetylamino)-3-(biphenyl-3-yl)-5-methoxy-7-phenyl-1,8-naphthyridine
CAS:1001911-63-2
Molecular Formula:C<sub>18</sub> H<sub>14</sub> BNO<sub>2</sub>
Molecular Weight:287.1
CAS:63503-60-6
