3652-90-2

  • Product Name2-Bromocarbazole
  • Molecular FormulaC12H8BrN
  • Molecular Weight246.1
  • Purity99%
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Product Details

Quick Details

  • CasNo: 3652-90-2
  • Molecular Formula: C12H8BrN
  • Purity: 99%

Pharmaceutical Intermediates 2-broMocarbazole 3652-90-2 In Stock

  • Molecular Formula:C12H8BrN
  • Molecular Weight:246.106
  • Vapor Pressure:0mmHg at 25°C 
  • Melting Point:253.0 to 257.0 °C 
  • Refractive Index:1.784 
  • Boiling Point:409.228 °C at 760 mmHg 
  • PKA:16.17±0.30(Predicted) 
  • Flash Point:201.294 °C 
  • PSA:15.79000 
  • Density:1.617 g/cm3 
  • LogP:4.08360 

2-BROMOCARBAZOLE(Cas 3652-90-2) Usage

Chemical Properties

White solid

Uses

Sensitive fluorogenic substrate for urokinase.

InChI:InChI=1/C12H8BrN/c13-8-5-6-10-9-3-1-2-4-11(9)14-12(10)7-8/h1-7,14H

3652-90-2 Relevant articles

Design, Synthesis, and Pharmacological Characterization of Carbazole Based Dopamine Agonists as Potential Symptomatic and Neuroprotective Therapeutic Agents for Parkinson's Disease

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3652-90-2 Process route

4'-bromo-2-nitrobiphenyl
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4'-bromo-2-nitrobiphenyl

2-bromo-9H-carbazole
3652-90-2

2-bromo-9H-carbazole

Conditions
Conditions Yield
With triphenylphosphine; In 1,2-dichloro-benzene; at 170 ℃; for 12h; Inert atmosphere;
89%
With triethyl phosphite; In 1,2-dichloro-benzene; at 80 - 150 ℃; Inert atmosphere;
75%
4'-bromo-2-nitrobiphenyl; With triethyl phosphite; at 160 ℃; for 2h;
With hydrogenchloride; In water; for 1h; Reflux;
67.6%
With triethyl phosphite; Inert atmosphere; Reflux;
65%
With triethyl phosphite; Inert atmosphere; Reflux;
65%
4'-bromo-2-nitrobiphenyl; With triethyl phosphite; Inert atmosphere; Reflux;
With hydrogenchloride; In water; at 80 ℃; for 3h;
65%
4'-bromo-2-nitrobiphenyl; With triethyl phosphite; Reflux; Inert atmosphere;
With hydrogenchloride; In water; at 20 - 80 ℃; for 3h; Inert atmosphere;
65%
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 10h; Inert atmosphere;
56%
With triethyl phosphite; at 150 - 160 ℃; for 30h; Inert atmosphere;
52%
With triethyl phosphite; at 150 - 160 ℃; for 30h; Inert atmosphere;
52%
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 18h; Inert atmosphere;
45%
With triethyl phosphite; at 150 ℃; for 6h;
44.38%
With triethyl phosphite; at 150 ℃; for 6h;
44.38%
With triethyl phosphite; at 150 ℃; for 6h;
44.38%
With triethyl phosphate; at 150 ℃; for 7h;
40.38%
With triethyl phosphite; for 24h; Reflux; Inert atmosphere;
40%
With triethyl phosphite; for 12h; Heating;
39%
With triethyl phosphite; at 160 ℃;
 
With triethyl phosphite;
 
With nitrogen; triphenylphosphine; In methanol; ethyl acetate; 1,2-dichloro-benzene;
 
4-bromo-2-nitro-1-phenylbenzene
70873-41-5

4-bromo-2-nitro-1-phenylbenzene

2-bromo-9H-carbazole
3652-90-2

2-bromo-9H-carbazole

Conditions
Conditions Yield
With triethylphosphine; for 12h; Reflux;
82.4%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
77%
With triphenylphosphine; In 1,2-dichloro-benzene; Inert atmosphere; Reflux;
77%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
74%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
74%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
74%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
74%
With triethyl phosphite; for 5h; Reflux;
72%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
72%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
71%
With triphenylphosphine; In 1,2-dichloro-benzene; at 200 ℃;
70%
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 8h; Inert atmosphere;
68%
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 8h; Inert atmosphere;
68%
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 8h; Inert atmosphere;
68%
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 8h; Inert atmosphere;
68%
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 8h; Inert atmosphere;
68%
With triethyl phosphite; In 1,2-dichloro-benzene; at 150 ℃; for 24h;
48%
With triethyl phosphite; In 1,2-dichloro-benzene; at 150 ℃; for 24h;
48%
With triethyl phosphite; at 160 ℃; for 18h;
 
With triphenylphosphine; In 1,2-dichloro-benzene; at 180 ℃; for 12h;
 
With triethyl phosphite; for 24h; Reflux;
 
With triethyl phosphite; for 10h; Reflux; Inert atmosphere;
500 mg
With triethyl phosphite; at 190 ℃; for 10h;
 
With triethyl phosphite; at 160 - 165 ℃; for 14h;
 
With triethyl phosphite; Reflux;
 
With triethyl phosphite; Inert atmosphere;
 

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