100124-06-9

  • Product NameDIBENZOFURAN-4-BORONIC ACID
  • Molecular FormulaC12H9BO3
  • Molecular Weight212.01
  • Purity99%
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Product Details

Quick Details

  • CasNo: 100124-06-9
  • Molecular Formula: C12H9BO3
  • Purity: 99%

High Quality Pharmaceutical Intermediates Dibenzofuran-4-boronic acid 100124-06-9

  • Molecular Formula:C12H9BO3
  • Molecular Weight:212.013
  • Appearance/Colour:Off-white to beige powder 
  • Vapor Pressure:0.011mmHg at 25°C 
  • Melting Point:286-291 °C(lit.) 
  • Refractive Index:1.485 
  • Boiling Point:438.5 °C at 760 mmHg 
  • PKA:8.04±0.30(Predicted) 
  • Flash Point:219 °C 
  • PSA:53.60000 
  • Density:1.34 g/cm3 
  • LogP:1.26580 

DIBENZOFURAN-4-BORONIC ACID(Cas 100124-06-9) Usage

Description

Dibenzofuran-4-boronic acid (DBFBA) is a boronic acid that has been used as a cross-coupling agent in the Suzuki coupling reaction. It has been shown to have low efficiency, but advances in this area have been made through the use of methanol extraction and photophysical properties. DBFBA is often coupled with imidazole derivatives to form anti-inflammatory compounds. The bond cleavage and hydrogen bonding properties of DBFBA make it a good target for drug synthesis.

Chemical Properties

off-white to beige powder

Isomeric SMILES B(C1=C2C(=CC=C1)C3=CC=CC=C3O2)(O)O
Exact Mass 212.0644743 g/mol
Monoisotopic Mass 212.0644743 g/mol
Complexity 259

InChI:InChI=1/C6H5BF2O2/c8-4-1-2-5(7(10)11)6(9)3-4/h1-3,10-11H

100124-06-9 Relevant articles

Deep blue organic light-emitting devices enabled by bipolar phenanthro[9,10-d]imidazole derivatives

Chen, Shuo,Wu, Yukun,Zhao, Yi,Fang, Daining

, p. 72009 - 72018 (2015)

Two blue fluorescent phenanthroimidazole...

Copper-Catalyzed Monoorganylation of Trialkyl Borates with Functionalized Organozinc Pivalates

Fu, Ying,Gou, Bei-Lei,Shi, Chun-Zhao,Du, Zhengyin,Shen, Tong

, p. 4253 - 4257 (2018)

Organozinc pivalates, a recently develop...

Facile Pd-Catalyzed Cross-Coupling of 2'-Deoxyguanosine O6-Arylsulfonates with Arylboronic Acids

Mahesh K. Lakshman, Paul F. Thomson, Mark A. Nuqui, John H. Hilmer, Nonka Sevova, and Bill Boggess

Org. Lett. 2002, 4, 9, 1479–1482

Increasing the boronic acid to 3.0 molar equiv … acid, use of 1.5 molar equiv of dibenzofuran-4-boronic acid resulted in a slow reaction (46 h). In this case increasing the boronic …

Compound, electronic element and electronic device

-

Paragraph 0160; 0161; 0163, (2020/05/01)

The invention provides a compound, an el...

Fused cyclic compound and organoelectroluminescent device comprising the compound

-

Paragraph 0105; 0124-0130, (2019/08/30)

PURPOSE: A condensed cyclic compound is ...

Synthesis method of dibenzofuran/thiophene-4-boric acid

-

Paragraph 0017, (2019/03/28)

The invention discloses a synthesis meth...

100124-06-9 Process route

4-dibenzofurylboronic acid
100124-06-9

4-dibenzofurylboronic acid

Conditions
Conditions Yield
With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 3h; Inert atmosphere;
In tetrahydrofuran; at -78 - 20 ℃;
79%
With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 3h; Inert atmosphere;
In tetrahydrofuran; at -78 - 20 ℃; Inert atmosphere;
79%
With n-butyllithium; In tetrahydrofuran; at -78 - 20 ℃; for 24h; Inert atmosphere;
In tetrahydrofuran; at -78 - 20 ℃; for 2h; Inert atmosphere;
With hydrogenchloride;
78.6%
Butyl-Li, 1) Dibenzofuran, Ae., 2) Trimethylborat, 3) wss. H2SO4;
 
dibenzofuran
132-64-9,214827-48-2

dibenzofuran

Triisopropyl borate
5419-55-6

Triisopropyl borate

4-dibenzofurylboronic acid
100124-06-9

4-dibenzofurylboronic acid

Conditions
Conditions Yield
dibenzofuran; With n-butyllithium; In tetrahydrofuran; hexane; at -68 - -20 ℃; for 1h; Inert atmosphere;
Triisopropyl borate; In tetrahydrofuran; hexane; at -68 - 20 ℃; for 5h;
With hydrogenchloride; In tetrahydrofuran; hexane; water; ethyl acetate;
 

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