123348-27-6

  • Product Name2-Bromo-7-iodo-9h-fluoren
  • Molecular FormulaC13H8BrI
  • Molecular Weight371.01
  • Purity99%
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Product Details

Quick Details

  • CasNo: 123348-27-6
  • Molecular Formula: C13H8BrI
  • Purity: 99%

Factory Supply 2-BroMo-7-iodo-9H-fluoren 123348-27-6 In Bulk Supply

  • Molecular Formula:C13H8BrI
  • Molecular Weight:371.015
  • Melting Point:178-180℃ 
  • Boiling Point:426.5±38.0 °C(Predicted) 
  • PSA:0.00000 
  • Density:1.988±0.06 g/cm3(Predicted) 
  • LogP:4.62490 

2-Bromo-7-iodo-9H-fluoren(Cas 123348-27-6) Usage

Uses

2-Bromo-7-iodofluorene is mainly used as intermediate of Ledipasvir. Ledipasvir is a potent inhibitor of HCV NS5A, a viral phosphoprotein that plays an important role in viral replication, assembly, and secretion.

 

123348-27-6 Relevant articles

One-photon photophysics and two-photon absorption of 4-[9,9-Di(2- ethylhexyl)-7-diphenylaminofluoren-2-yl]-2,2′:6′, 2″-terpyridine and their platinum chloride complexes

Ji, Zhiqiang,Li, Yunjing,Pritchett, Timothy M.,Makarov, Nikolay S.,Haley, Joy E.,Li, Zhongjing,Drobizhev, Mikhail,Rebane, Aleksander,Sun, Wenfang

, p. 2479 - 2491 (2011)

The synthesis, one-photon photophysics a...

123348-27-6 Process route

2-amino-7-bromofluorene
6638-60-4

2-amino-7-bromofluorene

2-bromo-7-iodofluorene
123348-27-6

2-bromo-7-iodofluorene

Conditions
Conditions Yield
ueber die Diazonium-Verbindungen;
 
2-iodo-9H-fluorene
2523-42-4

2-iodo-9H-fluorene

2-bromo-7-iodofluorene
123348-27-6

2-bromo-7-iodofluorene

Conditions
Conditions Yield
With 1,2-propylene cyclic carbonate; N-Bromosuccinimide; for 1.5h;
51%

123348-27-6 Upstream products

  • 6638-60-4
    6638-60-4

    2-amino-7-bromofluorene

  • 2523-42-4
    2523-42-4

    2-iodo-9H-fluorene

123348-27-6 Downstream products

  • 1245944-94-8
    1245944-94-8

    C49H39N

  • 1365541-05-4
    1365541-05-4

    2-bromo-9,9-dioctyl-7-(4-(1,2,2-triphenylethylenyl)phenyl)-9H-fluorene

  • 1365541-06-5
    1365541-06-5

    2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolane-2-yl)-9,9-dioctyl-7-(4-(1,2,2-triphenylethylenyl)phenyl)-9H-fluorene

  • 1421622-10-7
    1421622-10-7

    (E)-7-(2-(7-(bis(4-(2-(2-methoxyethoxy)ethoxy)phenyl)-amino)-9,9-bis(2-(2-methoxyethoxy)ethyl)-9H-fluoren-2-yl)vinyl)-9,9-bis(2-(2-methoxyethoxy)ethyl)-9H-fluorene-2-carbaldehyde

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