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Product Details
| 1-BROMO-2-CHLORO-3-NITROBENZENE Basic information |
| Product Name: | 1-BROMO-2-CHLORO-3-NITROBENZENE |
| Synonyms: | 1-BROMO-2-CHLORO-3-NITROBENZENE;oro-3-nitrobenzene;Benzene, 1-bromo-2-chloro-3-nitro-;1-BROMO-2-CHLORO-3-NITROBENZENE ISO 9001：2015 REACH |
| CAS: | 3970-37-4 |
| MF: | C6H3BrClNO2 |
| MW: | 236.45 |
| EINECS: | |
| Product Categories: | |
| Mol File: | 3970-37-4.mol |
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| 1-BROMO-2-CHLORO-3-NITROBENZENE Chemical Properties |
| Melting point | 57-60°C |
| Boiling point | 290.4±20.0 °C(Predicted) |
| density | 1.827±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,Room Temperature |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | Solid |
| color | Pale Yellow |
| Safety Information |
| HS Code | 2902900000 |
| 1-BROMO-2-CHLORO-3-NITROBENZENE Usage And Synthesis |
| Uses | 1-Bromo-2-chloro-3-nitrobenzene is a reagent used in pharmaceutical synthesis. Used in the synthesis of benzodiazepinone bromodomain inhibitor CPI-?637 which may be applicable to cancer therapies. |
| 1-BROMO-2-CHLORO-3-NITROBENZENE Preparation Products And Raw materials |
| Preparation Products | 3-bromo-2-chloroaniline-->1-Bromo-2-methoxy-3-nitro-benzene |
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Uses |
1-Bromo-2-chloro-3-nitrobenzene is a reagent used in pharmaceutical synthesis. Used in the synthesis of benzodiazepinone bromodomain inhibitor CPI-?637 which may be applicable to cancer therapies. |
InChI:InChI=1/C6H3BrClNO2/c7-4-2-1-3-5(6(4)8)9(10)11/h1-3H
The invention discloses a preparation me...
Compounds having activity as inhibitors ...
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2-chloro-3-nitrobezoic acid
1-bromo-2-chloro-3-nitrobenzene
| Conditions | Yield |
|---|---|
|
With bromine; mercury(II) oxide; In tetrachloromethane; for 3.5h; Heating; Irradiation;
|
96% |
|
With bromine; mercury(II) oxide; In tetrachloromethane; light;
|
96% |
|
With bromine; mercury(II) oxide; In tetrachloromethane; at 20 ℃; for 4.5h; Heating / reflux; Irradiation;
|
95% |
|
2-chloro-3-nitrobezoic acid; With mercury(II) oxide; In tetrachloromethane; for 0.25h; Photolysis; Reflux;
With bromine; for 4.5h; Reflux;
|
83% |
|
With bromine; mercury(II) oxide; In tetrachloromethane; at 87 ℃; for 3h; Heating / reflux; Irradiation;
|
67% |
|
With bromine; mercury(II) oxide;
|
2-bromo-6-nitroaniline
1-bromo-2-chloro-3-nitrobenzene
| Conditions | Yield |
|---|---|
|
With tert.-butylnitrite; copper dichloride; In acetonitrile; at 60 ℃; for 1h; Inert atmosphere;
|
86.2% |
|
With tert.-butylnitrite; copper dichloride; In acetonitrile; at 60 ℃; for 1h; Inert atmosphere;
|
82.7% |
|
Diazotization.Eintropfen der Diazoniumloesung in Kupferchloruerloesung;
|
|
|
2-bromo-6-nitroaniline; With sodium nitrate; sulfuric acid; acetic acid; at 25 - 35 ℃; for 0.5h;
With hydrogenchloride; copper(l) chloride; In water; at 70 ℃;
|
2-bromo-6-nitroaniline
1,2-dibromo-3-nitrobenzene
1-bromo-2-iodo-3-nitro-benzene
2-chloro-3-nitrobezoic acid
2-fluoro-3-bromonitrobenzene
1-(2-Bromo-6-nitro-phenyl)-piperidine
2-bromo-6-nitrophenyl methyl ether
2-bromo-N-tert-butyl-6-nitroaniline
CAS:56131-46-5
Molecular Formula:C6H5BrClN
Molecular Weight:206.47
Purity:99%
CAS:13029-09-9
Molecular Formula:C<sub>12</sub>H<sub>8</sub>Br<sub>2</sub>
Molecular Weight:312
