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Product Details
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Chemical Properties |
White powder |
| Canonical SMILES | CC1(C2=CC=CC=C2C3=C1C=C(C=C3)I)C |
| Wikidata | Q72483569 |
| Nikkaji Number | J446.537G |
| DSSTox Substance ID | DTXSID80452321 |
| Uses | 9,9-Dimethyl-2-iodofluorene is a chemical compound that finds applications in various fields due to its unique properties. Here is a description of its uses and applications in about 300 words:One of the primary uses of 9,9-Dimethyl-2-iodofluorene is in the field of organic synthesis. It serves as a valuable starting material for the preparation of diverse organic compounds. The compound contains an iodine atom attached to a fluorene backbone, which allows for the introduction of iodine into different chemical reactions. This versatility makes it useful for the synthesis of pharmaceutical intermediates, agrochemicals, and other complex organic molecules.In the pharmaceutical industry, 9,9-Dimethyl-2-iodofluorene is employed as a precursor in the synthesis of various drug candidates. The iodine atom can be substituted or transformed into other functional groups, altering the compound's pharmacological properties. 9,9-Dimethyl-2-iodofluorene is particularly useful in the synthesis of pharmaceuticals with aromatic or fluorinated structural motifs. It finds applications in the development of pharmaceutical compounds for cancer treatment, neurological disorders, and other therapeutic areas.Furthermore, 9,9-Dimethyl-2-iodofluorene plays a significant role in the field of materials science. It can be used as a building block for the creation of novel organic materials with enhanced properties. It's fluorene core provides good electron mobility, making it suitable for the preparation of organic semiconductors. These semiconducting materials are essential for the fabrication of organic electronic devices such as organic thin-film transistors (OTFTs) and organic light-emitting diodes (OLEDs). The introduction of iodine into the fluorene structure can further modify the electronic and optical properties of these materials.Moreover, the unique properties of 9,9-Dimethyl-2-iodofluorene make it suitable for use in chemical research and analysis. The iodine substituent can serve as a site for further functionalization or labeling, enabling the incorporation of radioactive isotopes or fluorescent probes. 9,9-Dimethyl-2-iodofluorene is often used as a labeled tracer in studies involving radiolabeling techniques, positron emission tomography (PET), or fluorescence imaging. It allows researchers to track specific molecular interactions, analyze metabolic pathways, and study the behavior of substances in biological or environmental systems.Although 9,9-Dimethyl-2-iodofluorene has many valuable applications, it should be handled with appropriate caution. 9,9-Dimethyl-2-iodofluorene is potentially harmful and should be used in a well-ventilated area with appropriate protective measures.In summary, 9,9-Dimethyl-2-iodofluorene is a versatile compound with applications in organic synthesis, pharmaceutical development, materials science, and chemical analysis. Its iodine substituent provides opportunities for functionalization and modification, which is crucial for tailoring the compound's properties to specific applications. Continued research and innovation in this area will likely uncover new uses and further enhance the compound's capabilities in various scientific and industrial fields. |
InChI:InChI=1/C15H13I/c1-15(2)13-6-4-3-5-11(13)12-8-7-10(16)9-14(12)15/h3-9H,1-2H3
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Three Bodipy dyes with strong absorptivi...
Fused iodoarenes, such as 2-iodo-9,9-dimethyl-9H-fluorene (1f) and 1-iodonaphthalene (1k), likewise reacted with iPrMgCl·LiCl to give the corresponding α-aryl-α-trifluoromethyl …
2-iodo-9,9-dimethyl-9H-fluorene (61). Furthermore, a variety of heteroaryl iodides were tested; 2-iodothiophene (62), 4-iodopyridine (63), 2-chloro-4-iodopyridine (64), 2-iodopyrazine (…
2-iodo-9H-fluorene
methyl iodide
2-iodo-9,9-dimethyl-9H-fluorene
| Conditions | Yield |
|---|---|
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2-iodo-9H-fluorene; With potassium tert-butylate; In tetrahydrofuran; at 0 ℃; for 0.166667h;
methyl iodide; In tetrahydrofuran; at 0 - 20 ℃;
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91% |
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2-iodo-9H-fluorene; With sodium hydroxide; benzyltrimethylammonium chloride; In water; dimethyl sulfoxide; at 20 ℃; for 3h;
methyl iodide; In water; dimethyl sulfoxide; at 20 ℃; for 3h;
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90% |
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2-iodo-9H-fluorene; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 1.5h;
methyl iodide; In tetrahydrofuran; for 2h;
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70% |
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2-iodo-9H-fluorene; With benzyltrimethylammonium chloride; sodium hydroxide; In water; dimethyl sulfoxide; at 20 ℃; for 3h;
methyl iodide; In water; dimethyl sulfoxide; at 20 ℃; for 3h;
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64% |
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With potassium tert-butylate; In dimethyl sulfoxide; at 0 ℃; for 0.166667h;
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2-iodo-9H-fluorene; With potassium tert-butylate; In tetrahydrofuran; dimethyl sulfoxide; at 25 ℃; for 0.333333h;
methyl iodide; In tetrahydrofuran; dimethyl sulfoxide; at 25 ℃; for 2.66667h;
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With potassium tert-butylate; In dimethyl sulfoxide; at 0 ℃; for 0.166667h; Schlenk technique; Inert atmosphere;
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With potassium methanolate; In N,N-dimethyl-formamide;
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With sodium methylate; In N,N-dimethyl-formamide; at 20 ℃; for 2h;
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21.5 g |
2-bromo-9,9-dimethyl-9H-fluorene
2-iodo-9,9-dimethyl-9H-fluorene
| Conditions | Yield |
|---|---|
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2-bromo-9,9-dimethyl-9H-fluorene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 24.5h; Inert atmosphere;
With iodine; In tetrahydrofuran; at -78 - 20 ℃; for 12h; Inert atmosphere;
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89% |
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2-bromo-9,9-dimethyl-9H-fluorene; With n-butyllithium; In tetrahydrofuran; at -78 - 20 ℃; for 24h; Inert atmosphere;
With iodine; In tetrahydrofuran; at -78 - 20 ℃; for 12h; Inert atmosphere;
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89% |
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2-bromo-9,9-dimethyl-9H-fluorene; With n-butyllithium; In tetrahydrofuran; at -78 - 20 ℃; for 24h; Inert atmosphere;
With iodine; In tetrahydrofuran; at -78 - 20 ℃; for 12h; Inert atmosphere;
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89% |
2-iodo-9H-fluorene
methyl iodide
2-bromo-9,9-dimethyl-9H-fluorene
9,9-dimethyl-N-(9,9-dimethyl-9H-fluoren-2-yl)-N-phenyl-9H-fluoren-2-amine
9,9-dimethyl-9H-fluoren-2-yl-2-boronic acid
N-(4-bromophenyl)-N-(9,9-dimethyl-9H-fluoren-2-yl)-9,9-dimethyl-9H-fluoren-2-amine
3-(N,N-bis(9,9-dimethylfluoren-2-yl)amino)anisole
CAS:605644-46-0
